Evaluation of the effect of botulinum toxin injection in aggravating or improving seborrheic dermatitis symptoms: A prospective, single‐arm clinical trial

Abstract Introduction Considering the proven therapeutic effect of botulinum toxin and pathophysiology seborrheic dermatitis, conflicting hypotheses have been put forward regarding injection this on improvement or exacerbation dermatitis. Because lack consistent studies investigating relationship, we decided to conduct study investigate local sebum production worsening dermatitis lesions. Method This was a prospective, single‐arm clinical trial that involved into 20 patients with complaints skin wrinkles simultaneous symptoms The conducted at dermatology clinic between March 2019 2021. Two important characteristics these were face scalp referral for remove facial wrinkles. Seborrheic Dermatitis Area Severity Index (SDASI) used determine severity symptoms. Results In an average age 40 years, despite decrease in scores all examined criteria study, 1 month after injection, no significant using seen patients’ ( p value >0.05). Conclusion Despite emphasis many effectiveness reducing activity sebaceous glands, use as modality control is not suggested by study. Conducting which location technique follow‐up intervals them are based standard other studies, suggestions made comparing results method current studies.